{"id":7435,"date":"2025-08-12T13:09:20","date_gmt":"2025-08-12T19:09:20","guid":{"rendered":"https:\/\/quantumlab.mx\/?page_id=7435"},"modified":"2025-08-14T16:05:23","modified_gmt":"2025-08-14T22:05:23","slug":"ph-d-jorge-cadena-iniguez","status":"publish","type":"page","link":"https:\/\/quantumlab.mx\/en\/scientific-equipment\/ph-d-jorge-cadena-iniguez\/","title":{"rendered":"Ph.D. Jorge Cadena \u00cd\u00f1iguez"},"content":{"rendered":"<p>Botanist and phytobiologist with more than two decades dedicated to the study, conservation and exploitation of genetic resources of Cucurbitaceae, particularly of the genus <em>Sechium<\/em> (<em>chayote<\/em>). He is a professor-researcher at the Colegio de Postgraduados and a reference in varietal characterization, phytochemistry oriented to bioactive compounds (e.g., cucurbitacins) and technology transfer to the agricultural sector. His work combines basic research (plant diversity and physiology) with translational applications in health and nutrition -including preclinical and human evidence on standardized extracts-, as well as editorial and genebank leadership.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Training and membership<\/h2>\n\n\n\n<p>D. in Botany (Colegio de Postgraduados), Master of Science in Botany (Colegio de Postgraduados) and Agricultural Engineer (UNACH). He is currently a professor-researcher at the Colegio de Postgraduados (Campus San Luis Potos\u00ed\/Montecillo) and directs\/coordinates academic networks in applied botany and genetic resources. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lines of research and key contributions<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Genetic resources and applied taxonomy of <em>Sechium<\/em><\/strong>: He is leading work that has made it possible to establish varietal descriptors (DUS) to distinguish and order the infraspecific variability in <em>S. edule<\/em>, with direct impact on conservation, registration and improvement. <a href=\"https:\/\/www.mdpi.com\/2223-7747\/11\/23\/3309\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li><strong>Germplasm banks and regulatory compliance<\/strong>has made a substantive contribution to the creation and management of the <strong>National Germplasm Bank of <em>Sechium edule<\/em> (BANGESe)<\/strong> in Mexico -recognized as the <strong>the only bank dedicated to chayote in the world<\/strong>- and the standardization of the accession passport. <\/li>\n\n\n\n<li><strong>Phytochemistry and bioactivity<\/strong>Part of their production demonstrates the antiproliferative and pro-apoptotic activity of standardized extracts of <em>Sechium<\/em> in tumor lines (e.g., leukemic and HeLa), as well as the relevance of metabolites (cucurbitacins) and phenolic matrices under genotype selection and breeding schemes. These findings have been published in peer-reviewed and open access journals. <a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/01635581.2015.989370?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">Taylor &amp; Francis Online<\/a><a href=\"https:\/\/www.mdpi.com\/2072-6643\/9\/8\/798\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9696414\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PMC<\/a><\/li>\n\n\n\n<li><strong>Translation to public health and nutrition<\/strong>Collaborates in clinical and population-based studies where controlled consumption of <em>Sechium<\/em> (in powder or formulations) shows effects <strong>antihypertensives, hypoglycemics, antioxidants and anti-inflammatories<\/strong> in older adults with metabolic syndrome, always within the framework of research and without implying therapeutic indications. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9220335\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PMC<\/a><\/li>\n\n\n\n<li><strong>Bioprospecting and genotype selection<\/strong>Participates in strategies for <strong>bioprospecting<\/strong> to identify varieties with higher content\/activity of compounds of interest, integrating agronomic, chemical and biological data for the development of lines with nutraceutical value. <a href=\"https:\/\/www.nature.com\/articles\/s41598-021-85676-7?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">Nature<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Projects and technical leadership<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>BANGESe (Mexico)<\/strong>Structuring and strengthening of the bank (collection, documentation and management), articulated with national plant genetic resources guidelines (SNICS) and accession passports. <a href=\"https:\/\/www.mdpi.com\/2223-7747\/11\/23\/3309\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li><strong>Networking and transfer<\/strong>Formation and coordination of interdisciplinary groups focused on the conservation and sustainable use of the <em>chayote<\/em>, with publications and technical materials that serve as a reference for producers and academics. <a href=\"https:\/\/ageconsearch.umn.edu\/record\/352197\/files\/JorgeCadena.pdf?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">ageconsearch.umn.edu<\/a><\/li>\n\n\n\n<li><strong>Editorial leadership<\/strong>Editor in chief\/responsible for <strong>Agro Productivity<\/strong> (Colegio de Postgraduados) and founder of <strong>Agro-Disclosure<\/strong>, platforms that disseminate applied science in agrobiology and rural development. <a href=\"https:\/\/revista-agroproductividad.org\/index.php\/agroproductividad\/about\/editorialTeam?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">revista-agroproductividad.org+1<\/a><a href=\"https:\/\/agrodivulgacion-colpos.org\/index.php\/1agrodivulgacion1\/about\/editorialTeam\" target=\"_blank\" rel=\"noreferrer noopener\">agrodivulgacion-colpos.org<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Role at Quantum Lab<\/h2>\n\n\n\n<p>In the context of Quantum Lab, Dr. Cadena provides a <strong>unique \u201clab to standard\u201d capability\u201d<\/strong> in vegetable matrices:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Standardization of plant biomass and extracts<\/strong>: Design of <strong>quality criteria<\/strong> (botanical identity, traceability, phytochemical markers, impurity limits) useful for auxiliary inputs or adjuvants of plant origin in our R&amp;D lines.<\/li>\n\n\n\n<li><strong>Compliance and access to genetic resources<\/strong>Alignment with <strong>Nagoya Protocol<\/strong> and best access\/benefit-sharing practices, ensuring responsible use of genetic resources and associated data. <em>(Operational link with banks such as BANGESe and published varietal descriptors).<\/em> <a href=\"https:\/\/www.mdpi.com\/2223-7747\/11\/23\/3309\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li><strong>Preclinical\/translational evaluation<\/strong>Consulting in <strong>test design<\/strong> in vitro\/in vivo screening of standardized extracts (safety\/activity), with critical reading of evidence in experimental oncology and metabolism.<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>Note: The evidence cited corresponds to basic, preclinical or early clinical research, and <strong>no<\/strong> equates to therapeutic indications or medical recommendations.<\/p>\n<\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\">Selected publications (access and reference)<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Varietal Descriptors for the Distinction of Underutilized Varieties of <em>Sechium edule<\/em><\/strong> (<em>Plants<\/em>, 2022). Establishes varietal descriptors with applications in conservation and improvement. <a href=\"https:\/\/www.mdpi.com\/2223-7747\/11\/23\/3309\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li><strong>Bioprospecting of <em>Sechium<\/em> spp. varieties...<\/strong> (<em>Scientific Reports<\/em>, 2021). Selection strategy for varieties with higher bioactive potential. <a href=\"https:\/\/www.nature.com\/articles\/s41598-021-85676-7?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">Nature<\/a><\/li>\n\n\n\n<li><strong>Fruit extract from a <em>Sechium edule<\/em> hybrid induce apoptosis in leukaemic cell lines...<\/strong> (<em>Nutrition and Cancer<\/em>, 2015). Evidence of selective cytotoxicity in leukemic lines. <a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/01635581.2015.989370?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">Taylor &amp; Francis Online<\/a><\/li>\n\n\n\n<li><strong>Sechium edule... \u201cBlack Pearl\u201d with antiproliferative potential in HeLa<\/strong> (<em>Nutrients<\/em>, 2017). Antiproliferative activity compared with cisplatin. <a href=\"https:\/\/www.mdpi.com\/2072-6643\/9\/8\/798\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li><strong>Antioxidant and Anti-Inflammatory Effect of <em>Sechium edule<\/em> in older adults with MetS<\/strong> (<em>Antioxidants<\/em>, 2022). Clinical outcomes in cardiometabolic parameters and inflammatory markers. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9220335\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PMC<\/a><\/li>\n\n\n\n<li><strong>Pharmacokinetics and Biological Activity of Cucurbitacins<\/strong> (<em>Molecules\/Life Sciences interface<\/em>, 2022). Co-authored review on pharmacokinetics and bioactivity of cucurbitacins. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9696414\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PMC<\/a><\/li>\n\n\n\n<li><strong>Chayote Fruit... Metabolomic characterization<\/strong> (study in orchards of <strong>BANGESe<\/strong>, 2022-2023). Integrate metabolomics and origin of plant material in national bank. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9823722\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PMC+1<\/a><\/li>\n\n\n\n<li><strong>Limitations in the growth and development of chayote<\/strong> (<em>Notulae Botanicae Horti Agrobotanici<\/em>, 2024). Updates physiological and agronomic limitations for <em>Sechium<\/em>. <a href=\"https:\/\/www.notulaebotanicae.ro\/index.php\/nbha\/article\/view\/14002?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">Notulae Botanicae<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Disclosure and editorials<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Agro Productividad (Managing Editor\/Editor-in-Chief)<\/strong>Monthly magazine of the Colegio de Postgraduados; multiple issues reflect its editorial responsibility. <a href=\"https:\/\/revista-agroproductividad.org\/index.php\/agroproductividad\/about\/editorialTeam?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">revista-agroproductividad.org+1<\/a><a href=\"https:\/\/www.colpos.mx\/wb_pdf\/Agroproductividad\/2017\/AP-10-11-2017_ISSN-e.pdf?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">colpos.mx<\/a><\/li>\n\n\n\n<li><strong>Agro-Disclosure (Founder)<\/strong>bimonthly journal of technical-scientific communication; the official website acknowledges his role as founder.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Bot\u00e1nico y fitobi\u00f3logo con m\u00e1s de dos d\u00e9cadas dedicadas al estudio, conservaci\u00f3n y aprovechamiento de recursos gen\u00e9ticos de Cucurbitaceae, particularmente del g\u00e9nero Sechium (chayote). Es profesor-investigador del Colegio de Postgraduados y referente en caracterizaci\u00f3n varietal, fitoqu\u00edmica orientada a compuestos bioactivos (p. ej., cucurbitacinas) y transferencia tecnol\u00f3gica al sector agr\u00edcola. Su trabajo combina investigaci\u00f3n b\u00e1sica (diversidad [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":6176,"parent":7373,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_joinchat":[],"footnotes":""},"class_list":["post-7435","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/pages\/7435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/comments?post=7435"}],"version-history":[{"count":0,"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/pages\/7435\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/pages\/7373"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/media\/6176"}],"wp:attachment":[{"href":"https:\/\/quantumlab.mx\/en\/wp-json\/wp\/v2\/media?parent=7435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}